Skyler's frustration with Walt's secrecy boils over; Jesse is dealt a devastating blow that leads him down a path of self-destruction, and only Walt us willing to help him; and a grief-stricken Donald experiences more tragedy.
A new addition joins the White family as Walter Jr. attempts to help out his struggling family by launching a new Web site. Elsewhere, Jesse's addiction worsens and his relationship with Jane begins to negatively impact Walt and her father (John de Lancie).
Saul suggests a new business partner. Skyler discovers something shocking at work. Jesse tells Jane about his job.
With Walt's disease in remission, the Whites throw a party for all those who've supported him through the ordeal, but the mood is ruined when Walt and Hank argue. Skyler is worried about Walt's emotional state as Walt tries various home improvement projects to occupy himself. Jane continues her relationship with Jesse but keeps this secret from her father.
Walt interrupts Jesse's weekend plans to inform his partner they'll have to cook for four days straight, or risk losing their batch of methylamine.
When Badger finds himself in trouble with the law, Walt and Jesse seek the legal advice of a shady attorney, Saul Goodman. The DEA believe they may have finally caught up with the elusive 'Heisenberg.' Hank returns to Albuquerque, but his troubled mental state and demeanor cause Marie to worry.
Rumors fly about Jesse's recent actions as he and Walt discuss expanding their business into new territories. Hank struggles to fit in with his new co-workers in El Paso. Skyler pursues a new job opportunity that reconnects her with a former colleague. Jesse gets to know his landlord, Jane.
Walt's secret is in jeopardy when Skyler thanks Gretchen for paying for his treatment.
Hank suffers from the aftermath of his encounter with Tuco. Meanwhile, Jesse hires a crew to get their product out on the streets.
Walt attempts to reconnect with his family, while Jesse struggles to rebuild his life.